Blueprint is a CSS framework, which aims to cut down on your CSS development time. It gives you a solid CSS foundation to build your project on top of, with an easy-to-use grid, sensible typography, and even a stylesheet for printing.
I saw this a couple of days ago and decided this may be just the trigger to get me to redesign an old phpWebsite theme. The old theme works but it is kind of quirky since it started out as a table based layout theme. It could benefit from a redesign from the ground up. I have been yearning to redesign and clean up the theme for some time. Most of my theme ideas come from WordPress Themes so I was looking at porting one or more WordPress themes I like over to phpWebsite. It is debatable whether it makes sense to port over the themes since I could recreate the site in WordPress in about the same amount of time. I will mull over this a little while longer.